IP3 receptor signaling and endothelial barrier function
نویسندگان
چکیده
منابع مشابه
Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca2+ Signaling in Endothelial Cells
The mechanisms by which the microtubule cytoskeleton regulates the permeability of endothelial barrier are not well understood. Here, we demonstrate that microtubule-associated end-binding protein 3 (EB3), a core component of the microtubule plus-end protein complex, binds to inositol 1,4,5-trisphosphate receptors (IP3Rs) through an S/TxIP EB-binding motif. In endothelial cells, α-thrombin, a p...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2017
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-017-2624-8